Melatonin and its agonists: an update.

نویسندگان

  • Josephine Arendt
  • Shantha M W Rajaratnam
چکیده

The pineal hormone melatonin is able to shift the timing of circadian rhythms, including the sleep-wake cycle, and to promote sleep. Melatonin agonists with similar properties have therapeutic potential for the treatment of circadian rhythm sleep disorders. Depression is specifically targeted by agomelatine, which is also a serotonin-2C (5-HT(2C)) antagonist.

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عنوان ژورنال:
  • The British journal of psychiatry : the journal of mental science

دوره 193 4  شماره 

صفحات  -

تاریخ انتشار 2008